NeuroMarseille – Visite 360° – Centre d’Exploitation Métabolique par Résonance Magnétique (CRMBM)On December 13, 2019 by Raul Dinwiddie
Hello, my name is Jean-Philippe Ranjeva, I am a professor of Neuroscience at Aix-Marseille University and I lead the
“Central Nervous System” group at the Magnetic, Biological and
Medical Resonance Center, which is a Joint Research Unit of CNRS
and Aix-Marseille University. More particularly, you are here on the hospital site of the CEMEREM laboratory, which is a service
of Marseille Hospitals, on which three MRIs are installed,
dedicated to exploring the central nervous system, muscles and human heart with three machines with a 1.5 tesla
magnet, 3 teslas and the machine you will discover thanks to this sequence, which is a 7 tesla MRI, full body,
which is the second in France and the only one that can do both imaging of the brain, the spinal cord, the muscles and the heart.
This laboratory aims to develop new MRI methods and to define new biomarkers, which allow us to better understand human pathologies. In my research group, we are
trying to identify new biomarkers that allow us to better understand the
pathophysiology of neurological diseases such as multiple sclerosis, epilepsy
or spinal cord injuries. To do so, we have access through the 7T
MRI to an improved spatial resolution, down to 500 microns, which allows us to obtain very important information on cortical sublayers.
In addition, this signal gain also gives us access to brain metabolism and ionic homeostasis, notably thanks to sodium MRI, which is
a speciality of the laboratory. We couple these morphological and
metabolic analyses to functional and network organization analyses obtained through diffusion MRI,
and to functional connectivity obtained by functional MRI. This allows us to understand brain reorganization in the
presence of various types of lesions, which can be either focal or diffuse.
Now, please discover this 7T MRI in an interactive way. You can click on the different areas to open informative popups. Thank you.